• SN EN ISO 9001 & 13485
  • Easy reorder
  • No minimum order value
  • Fast shipping

EasyPGX ready KRAS kit, 48 tests

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Delivery time approx. 5 working days

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Detection of the main mutations of exon 2, of exon 3 and of exon 4 of the gene KRAS using 8 oligo mixes. Each mix allows the co-amplification of one or more mutated alleles plus an endogenous control gene. A specific oligo control mix enables the evaluation of the quality and the quantity of the DNA in each sample.

  • 11003907
  • RT021
  • Description:

    Main features
    Detection of the main mutations of exon 2 (codons 12, 13), of exon 3 (codons 59, 61) and of exon 4 (codons 117, 146) of the gene KRAS using 8 oligo mixes. Each mix allows the co-amplification of one or more mutated alleles plus an endogenous control gene. A specific oligo control mix enables the evaluation of the quality and the quantity of the DNA in each sample.


    Controls
    The kit is provided with the following controls:
    Positive control sample containing a mixture of synthetic DNA sequences that correspond to each mutation detected by this kit in a background of wild-type genomic DNA;
    Negative control.


    Sensitivity
    The kit allows the detection of low percentages of mutated allele in presence of high amounts of wild-type genomic DNA by real-time amplification with sequence-specific probes marked with FAMb and HEX. LOD down to 0.5%.
    Starting material
    The kit allows the analysis of DNA extracted from fresh, frozen, formalin-fixed paraffin-embedded (FFPE) tissues and plasma*.
    *Please note that extraction from plasma is sold separately (cat.no. H8040)

    • Transport temperature from:
      2 °C
    • Transport temperature to:
      8 °C
    • Dangerous preparation according to 67/548/EEC:
      no
    • Dangerous preparation according to 99/45/EEC:
      no
    • Ready to use reagent:
      no
    • Automatisations suitable:
      no