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[Glu1]-Fibrinopeptide B human


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[Glu1]-Fibrinopeptide B human

  • 11005831
  • F3261-1MG
  • Description:

    Synonyms CAMKP, CaMKPase, FEM-2, POPX2, hFEM-2

    Species Human (9647) , Species Mouse (68606) , Species Rat (287931) , Species cow (618210) , Species sheep (101114979) , Species domestic guinea pig (100715460) , Species naked mole-rat (101699789) , Species Zebrafish (553757) , Species Horse (100057884) ,Species domestic cat (101087876) , Species dog (486448) , Species chicken (416772)

    Summary: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]

    • Package Contents:
    • Storage temperature from:
      -20 °C
    • Storage temperature to:
      -20 °C
    • Transport temperature from:
      -20 °C
    • Transport temperature to:
      -20 °C
    • Dangerous preparation according to 67/548/EEC:
    • Dangerous preparation according to 99/45/EEC:
    • Ready to use reagent:


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